Medical Director - Neurodegenerative Diseases (Alzheimer's Disease)

Contract | Outside IR35
Hybrid - 2 days per week onsite (Welwyn Garden City area)

The Opportunity

An innovative global biopharmaceutical organisation is seeking an experienced Medical Director - Neurodegenerative Diseases to support late-stage clinical development programmes in CNS, with a primary focus on Alzheimer's disease.

This role offers the opportunity to contribute to pivotal Phase III programmes aimed at addressing significant unmet medical needs in neurodegeneration. You will play a central role in translating cutting-edge science into high-impact clinical strategies, helping to bring potentially transformative therapies to patients.

This is a high-visibility, cross-functional leadership position within a global matrix environment.

Key Responsibilities

• Support the design and execution of global clinical development strategies across all phases, with strong emphasis on Phase III programmes

• Provide medical monitoring for ongoing interventional clinical trials

• Contribute to protocol development, study design, and data interpretation

• Partner closely with cross-functional teams including Clinical Operations, Safety, Biostatistics, Regulatory Affairs, Clinical Pharmacology, Biomarkers, and Research

• Support preparation for regulatory interactions and health authority engagements

• Participate in advisory boards and engage with external investigators and key opinion leaders

• Translate clinical data into strategic development decisions

Candidate Profile

Essential

• MD or MD/PhD (medical degree required)

• Minimum 5 years' experience in longitudinal clinical research, including hands-on clinical trial experience (industry or academic setting)

• Strong experience supporting or leading Phase II-III development programmes, with particular focus on Phase III

• Experience in medical monitoring of interventional studies

• Proven ability to work effectively within global, cross-functional matrix teams

• Experience interfacing with regulatory authorities and external stakeholders

• Excellent written and verbal scientific communication skills

Desirable

• Direct experience in neurodegenerative diseases, particularly Alzheimer's disease

• Experience designing late-stage CNS development strategies

• Prior experience within a global pharmaceutical or biotechnology organisation

• Involvement in regulatory submissions

• Peer-reviewed publications in neurology or neurodegeneration

Who This Role Would Suit

We are seeking a medically trained physician who:

• Brings strong late-stage CNS clinical development expertise

• Is confident in medical monitoring and protocol design

• Operates effectively in a complex, global matrix structure

• Is comfortable engaging with regulators and external experts

• Combines scientific rigour with strategic thinking

Work Arrangement & Contract Details

• Contract position

• Outside IR35

• Hybrid working: 2 days per week onsite in the Welwyn Garden City area

If you are passionate about advancing innovation in neurodegenerative disease and want to contribute to high-impact late-stage programmes, we encourage you to apply.