Senior Director, Medical Affairs CNS

Join a Leading Force in Gene Therapy as Senior Director, Global Medical Affairs - CNS

This is a unique opportunity to join a pioneering, fully integrated gene therapy company driving life-changing innovations across a range of neuromuscular and central nervous system (CNS) disorders. The organisation is independently operated with global headquarters in the US and a strong European presence, combining cutting-edge science with industry-leading manufacturing capabilities. At the core of its mission is the development of transformative molecular medicines for patients with few or no treatment options.

The company is deeply committed to scientific excellence, clinical impact, and fostering a collaborative, values-driven culture. With a robust clinical pipeline and a track record of scientific breakthroughs, this business offers a compelling opportunity for an experienced medical leader to shape global medical strategy for its high-impact CNS programs, including Parkinson's disease and multiple system atrophy.

Your role as Senior Director, Global Medical Affairs - CNS

• Act as the senior medical affairs leader for CNS programs, reporting to the SVP of Global Medical Affairs and working closely with cross-functional teams across clinical development, commercial, and regulatory affairs

• Co-lead CNS brand strategy sub-teams and drive integrated medical affairs planning in alignment with clinical and commercial goals

• Develop and oversee global Medical Affairs strategies that support patient access, data generation, and product differentiation

• Lead scientific engagement with external experts, advocacy organisations, and healthcare professionals across major markets

• Manage congress activities, advisory boards, publication strategy, and external scientific communications for the CNS therapeutic area

• Guide internal teams on therapeutic area knowledge, scientific messaging, and data dissemination

• Oversee external agency partnerships and ensure medical content is scientifically accurate and aligned with global objectives

• Collaborate on real-world evidence generation, health economics studies, and post-marketing activities to support market uptake and product positioning

• Represent the company at key medical and scientific conferences globally

• Manage CNS medical affairs budgets and lead cross-functional governance meetings in alignment with program timelines

Experience and qualifications for the Senior Director, Global Medical Affairs - CNS role

• Medical degree (MD or equivalent) with clinical training in neurology or neurosurgery strongly preferred; PharmD candidates with relevant CNS experience will be considered

• At least 12 years of relevant experience, including 5+ years in medical affairs or related commercial roles within the pharmaceutical or biotech sector

• Proven success in medical affairs leadership roles supporting CNS or neurology-based programs, ideally across multiple clinical stages

• Track record of developing and executing global publication and medical strategy plans

• Strong understanding of the drug development process and lifecycle management, from early research through launch and commercialisation

• Experience leading cross-functional initiatives and acting as a key medical voice within a matrixed global organisation

• Skilled in developing high-impact scientific engagement strategies and external communication packages

• Comfortable presenting to executive leadership and aligning complex programs with organisational goals

• Experience managing external vendors, medical writers, and scientific agencies

• Willingness to travel

Perks and benefits

• Competitive base salary and bonus structure

• Opportunity to lead the medical strategy for a globally significant clinical pipeline

• Remote working

• Influence over next-generation gene therapies in CNS disorders

• Inclusive, values-led company culture with a focus on innovation and collaboration

• Direct impact on patient communities through the development of novel therapies

• Global exposure with career development opportunities across geographies and functions

.